The effects of long-term aerobic and resistance combined exercise training on cardiovascular risk factors and oxidative stress in stroke patients

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doi:2010.19.3.231

Exerc Sci > Volume 19(3); 2010 > Article

Exercise Science 2010;19(3): 231-246. doi: https://doi.org/10.15857/ksep.2010.19.3.231

장기간의 복합운동이 남녀 뇌졸중 환자의 심혈관 위험요인과 산화스트레스 관련 지표의 변화에 미치는 영향

신윤아¹, 김효중²

¹단국대학교
²서울대학교

The effects of long-term aerobic and resistance combined exercise training on cardiovascular risk factors and oxidative stress in stroke patients

ABSTRACT

The purpose of this study was designed to determine the effect of 24weeks aerobic and resistance combined exercise training on cardiovascular risk factors, oxidative stress in stroke patients and the association between cardiovascular risk factors and markers of oxidative stress. Fifty stroke patients(male: 27, female: 23) volunteered for this study. Stroke patients participated in a supervised training program for 24 weeks(3days a week, warm-up 5minutes, exercise 80minutes, and colo-down 5minutes) consisting of aerobic exercise(75% HRmax, 13~14RPE) and resistance exercise(65~75% RM, 10~15RM). After exercise training, body weight(p<.05), WHR(p<.001), and total cholesterol(p<.01) were significantly decreased in all exercise groups. High density lipoprotein levels(p<.05) were significantly increased and cardiovascular risk factor number(p<.01) were significantly decreased after exercise training. Ox-LDL, ox-LDL/LDL(p<.001) and ferritin concentrations(p=.053) were significantly after exercise training. However, there was no difference between male and female stroke patients. Totally, a significant positive correlation between ox-LDL, total cholesterol(r=.575, p<.001) and triglyceride(r=.338, p<.05) was observed. The ox-LDL/LDL were a significant positive correlation with triglyceride(r=.476, p<.001). Ferritin concentration was a significant positive correlation with body weight(r=.409, p<.01), body mass index(r=.316, p<.05), and fasting glucose levels(r=.458, p<.005) and CRP levels was a significant positive correlation with body weight(r=.292, p<.05) and body mass index(r=.359, p<.01). Moreover, ferritin concentration was a significant positive correlation with CRP levels(r=.298, p<.05). These findings indicate that markers of oxidative stress affect the cardiovascular risk factors, especially in male stroke patients. Taken together, the aerobic and resistance combined exercise programs were effect on the reduction of cardiovascular risk factors, oxidative stress and the prevent of recurrent stroke

Key words: stroke patient, cardiovascular risk factors, oxidative stress, combined exercise