| 지구성 운동이 중추신경 전달물질 활성에 미치는 영향 |
| 김영표 |
| 한남대학교 |
| Effects of endurance exercise on expression of central neurotransmitters of rats |
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| ABSTRACT |
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Effects of endurance exercise on expression of central neurotransmitters of rats. Exercise Science, 13(1): 55-64, 2004. The effect of endurance exercise on expression of central neurotransmitters of rats was investigated via immunohistochemistry. Male Sprague-Dawley rats were randomly divided into the control, low-intensity exercise(LE), moderate-intensity exercise(ME), and 1, 3, 7, 14, 28-days -exercise groups. The LE consisted with running at speed of 3m/min(5 min), 5m/min(5 min), then 8m/min for the last 20 min, and the ME was made with running at speed of 8m/min(5 min), 11m/min(5 min), then 14m/min for the last 20 min once a day. In the present results, tryptophan hydroxylase(TPH) expression in the ME was significantly increased compared to the LE, in the 14 and 28-days -exercise groups, in the 28-days-exercise group was than higher the control and different exercise period groups in the LE, and in the 14, 28-days-exercise groups was than higher the control and different exercise period groups in the LE.. Tyrosine hydroxylase(TH) expression of the 28-days -exercise group in the ME was significantly decreased compared to the control, different exercise period groups, and in the LE. The present results demonstrate that exercise intensity and duration is an important factor on the regulation of expression of central neurotransmitters in the brain and that the endurance exercise may prevent central fatigue by regulating TPH and TH expression. |
| Key words:
endurance exercise, TPH, TH, 5-hydroxytryptamine(5-HT), serotonin |
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