The effect of aerobic exercise on plasma endothelin-1 levels and vascular compliance

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doi:2007.16.4.345

Exerc Sci > Volume 16(4); 2007 > Article

Exercise Science 2007;16(4): 345-354. doi: https://doi.org/10.15857/ksep.2007.16.4.345

유산소운동이 혈장 Endothelin-1 농도 및 혈관탄성에 미치는 영향

이은희¹, 김영준¹, 장성동², 김주홍¹, 문성진¹, 최진관¹

¹동아대학교
²동주대학교

The effect of aerobic exercise on plasma endothelin-1 levels and vascular compliance

ABSTRACT

Lee, E.H., Kim, Y.J., Jang, S.D., Kim, J.H., Moon, S.J., Choi, J.K.. The Effect of Aerobic Exercise on Plasma Endothelin-1 Levels and Vascular Compliance. Exercise Science. 16(4): 345-354, 2007. The purpose of this study was to investigate the effects of 8 weeks aerobic exercise on plasma lipids, Endothelin-1 and vascular compliance in middle aged males(N=16). Subjects who participated in this study were divided into two groups. One was a exercise group(N=8, 47.4±4.87 years old) and a control group(N=8, 47.1±2.90 years old). Exercise group performed treadmill 1 hour a day, 3 times a week for 12weeks. We measured the changes of Endothelin-1, Cholesterol, HDL-C, LDL-C and Triglyceride in blood by collecting blood and Vascular compliance by PWV 3.0(K_M tec) before and after 12 weeks. The results of this study were as follow: Endothelin-1 was significantly(p<.05) decreased in exercise group, but there was no change in control group after 12weeks. Vascular compliance of all(right wrist, left wrist, right ankle, left ankle) were significantly(p<.05, p<.01) increased in exercise group, but there was no change in control group after 12weeks. Regular aerobic exercise is effective in improvement of vein circulatory system improving vascular compliance as well as decrease Endothelin-1 that is strong vein contracting compound that is created in vascular endothelial cell to middle age males who retrogression change of vascular begin.

Key words: aerobic exercise, Endothelin-1, vascular compliance