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Exercise Science 2005;14(2): 143-152. |
| 점프 트레이닝이 난소적출 쥐의 골 재형성에 미치는 영향 |
| 권기욱, 정희정, 김영주, 오재근, 이정필, 김호성, 신영오 |
| 한국체육대학교 |
| To examine the effects of jump training on bone remodeling in OVX rats |
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| ABSTRACT |
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Kwon, K.W., Kim, Y.J., Kim, H.S., Jung, H.J., Lee, J.P., Oh, J.K. To examine the effects of jump training on bone remodeling in OVX rats. Exercise Science, 14(2): 143-152, 2005. To examine the effects of jump training on bone remodeling in OVX rats, fifty six female Sprague-Dawley rats were sham-operated (Sham) and ovariectomized (OVX) at the age of six weeks. The rats were divided randomly into the following four groups: sham-control (Sham-Cont; n=14), sham-exercise (Sham-Exc; n=14), OVX-control (OVX-Cont; n=14), and OVX-exercise (OVX-Exc; n=14). Jump training was no significant change in body weight. However, the final body weights of the OVX groups significantly increased compared to the Sham groups(p<.001). Histology in OVX-Exc showed increase in width and number of trabecular bone compared to OVX-Cont but they were somewhat smaller than the Sham groups. The OPG protein expression level was decreased after four weeks and eight weeks in OVX-Cont, compared to Sham-Cont. Jump training was increased the OPG protein expression level in OVX groups. The OPG protein expression level after jump training did not changes in the Sham groups. Also the OPG protein expression level in OVX-Exc was increased as much as in the Sham groups. Jump training did not affect the RANKL protein expression level in both the Sham groups and OVX groups. In the Sham groups, jump training did not affect OPG/RANKL ratio, but in the OVX groups, jump training did affect the increase of OPG/RANKL ratio. Therefore, in jump training, histology indicated that there were beneficial effects on bone and that OPG protein expression levels were affected by jump training. |
| Key words:
ovariectomized rats, histology, OPG expression, RANKL expression |
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